In a study to evaluate the importance of different factors on the development of cirrhosis among hepatitis C virus positive individuals, 35 out of 79 individuals without cirrhosis reported alcohol abuse compared to 10 out of 20 individuals with cirrhosis (p-value = 0.84). Which of the following statements is true?
A. The paired t-test can be used to analyze these data.
B. An appropriate null hypothesis is: there is an equal number of alcohol abusers in the population of individuals with and without cirrhosis.
C. The p-value of 0.84 indicates there is no difference in the observed rates of alcohol abuse in the two groups.
D. The chi-square test requires the calculation of observed frequencies in each cell of the contingency table created from the results.
E. The 95% confidence for the difference in proportions would exclude zero.