CC,a 72 year old female,omplains lo the pharmacist that her stomach has been bothering her recently. Current
medications include: levothyroxine 0. 1 mg po daily (x 30 years), acetaminophen 500 mg po qid
（x5 months),atorvastatin 40 mg po hs (x 4 years), ibuprofen 400 mg po tid prn for joint pain (x 2 months) and
zopicione 3 75 mg po hs pm (x 3 months). Which of the following drug therapy problems is most likely contributing to
CC's recent symptoms?

A.Too high a dosage of atorvastatin
B.Too high a dosage of zopiclone
C.Use of ibuprofen without gastroprotection
D.Drug interaction between atorvastatin and zopiclone