The nurse is caring for a patient receiving high-dose methotrexate (MTX) (Rheumatrex, Trexall) therapy. What intervention is a priority for this patient?
A. Administering bleomycin immediately after treatment with MTX
B. Infusing IV dextrose at 100 mL/hr throughout the drug therapy
C. Encouraging oral fluids to 4 L/day while being treated with MTX
D. Administering leucovorin within 2 days of treatment with MTX