Repeated administration of some drugs will lead to a decrease in their effectiveness, an occurrence known as drug tolerance. When this occurs, doctors may need to increase the dosage in order to continue therapy. What is true of this increase?
A.The increase in dosage will be the same for different patients
B.Drugs of a certain type will exhibit the same drug tolerance rates
C.The dosage will increase by the same amount each time the patient reaches tolerance
D. The dosage increase is directly proportional to the initial dose