Prevention of ___________________ has been aided by immunizations. ___________________ and ___________________ vaccination have been effective in preventing invasive infections caused by S. pneumoniae and H. influenzae, respectively, and vaccination for viral pathogens (e.g., influenza virus, varicella virus) has helped lower the incidence of invasive secondary infections caused by bacterial pathogens, such as S. aureus and S. pyogenes. In the hospital setting, prevention of ___________________ revolves around minimizing iatrogenic infections from indwelling intravascular catheters and other invasive devices by following recommended infection control practices.