Following the administration of a dose, the initial plasma concentration and the plasma concentration at 5 h are reported to be 5.3575 µg/mL and 1.6879 µg/mL, respectively. Determine the elimination half-life (t 1/2 ) and the plasma concentration at 8 h following the administration of a 10 mg/kg dose.
A) t1/2 =2.94 h, Concentration at 8 h = 0.7687 µg/mL
B) t 1/2 =3.12 h, Concentration at 8 h = 0.6945 µg/mL
C) t 1/2 =2.82 h, Concentration at 8 h = 0.8204 µg/mL
D) t 1/2 =3.00 h, Concentration at 8 h = 0.7263 µg/mL