In terms of pathophysiological changes, Sepsis often begins with an infection that triggers the immune system to release chemicals into the bloodstream to fight the invading pathogens. The immune response becomes dysregulated, leading to a systemic inflammatory response. Write with citation and references

A) Describe the role of cytokines in sepsis progression (Smith et al. , 2019)
B) Explain the role of bacterial endotoxins in sepsis onset (Jones & Brown, 2020)
C) Discuss the impact of sepsis on organ function (Lee et al. , 2018)
D) Outline treatment strategies for sepsis management (Johnson & White, 2021)