How would a genetic defect causing increased exocytosis (above normal) be harmful?
a) Increased exocytosis of insulin could lead to constantly low blood sugar levels, resulting in hypoglycemia and potential loss of consciousness or seizures.
b) The increased demand on pancreatic beta cells to produce and release more insulin could lead to their exhaustion and eventual failure, resulting in diabetes.
c) Rapid and excessive release of insulin could lead to a continuous state of hyperinsulinemia, which may contribute to insulin resistance and metabolic syndrome.
d) The precise regulation of insulin release is crucial for maintaining stable blood sugar levels, and a genetic defect causing increased exocytosis could disrupt this balance, leading to severe complications such as diabetic ketoacidosis or hypoglycemic coma.