apoptosis can occur in response to what?
a) Signaling in normal development
b) Cell shape, when cells adopt an inappropriate shape
c) Signaling in normal development and cellular damage
d) Signaling in normal development, cellular damage, cell size, particularly when cells grow to a much larger than average size
e) Signaling in normal development, cellular damage, cell size, particularly when cells grow to a much larger than average size, and cell shape, when cells adopt an inappropriate shape