The basic difference between spermatogenesis and oogenesis is that ________. the basic difference between spermatogenesis and oogenesis is that ________. spermatogenesis involves mitosis and meiosis, but oogenesis involves meiosis only the mature ovum is n, while the sperm is 2n during spermatogenesis two more polar bodies are produced in oogenesis, one mature ovum is produced, and in spermatogenesis four mature sperm are produced from the parent cell