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Jose has an extra chromosome on the twenty-first pair of chromosomes. the disorder was once referred to as mongolism. this will cause him to have

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This will cause him to have Down syndrome.  
The most common form of Down syndrome is known as trisomy 21, a condition where individuals have 47 chromosomes in each cell instead of 46. Trisomy 21 is caused by an error in cell division called nondisjunction. This leaves a sperm or egg cell with an extra copy of chromosome 21 before or at conception. 

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