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The stretch of the integral protein within the hydrophobic interior of the bilayer is also hydrophobic, made up of non-polar amino acids. Like the lipid bilayer, the exposed ends of the integral protein are hydrophilic. When a protein crosses the lipid bilayer it adopts an alpha-helical configuration.

The type of amino acids that will be present where integral proteins attach to cell membranes are non-polar amino acids.

What is a non-polar amino acid?

An amino acid is a building block of proteins and non-polar amino acids have R-groups composed of hydrocarbons.

  • These amino acids (non-polar amino acids) can bind to the phospholipids of the cell membrane, which are hydrophobic.

In conclusion, the type of amino acids that will be present where integral proteins attach to cell membranes are non-polar amino acids.

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