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Why is glycolysis described as having an energy investment phase and an energy payoff phase? Why is glycolysis described as having an energy investment phase and an energy payoff phase? Early steps consume energy from ATP and NADH, and later steps store an equal amount of energy in ATP and NAD+. Early steps consume energy from ATP, and later steps store an increased amount of energy in ATP and NADH. Early steps consume energy from ATP and NADH, and later steps store an increased amount of energy in ATP and NADH. Early steps consume energy from ATP and NADH and later steps store an increased amount of energy in ATP. Early steps consume energy from NADH, and later steps store an increased amount of energy in ATP and NADH.

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The answer is;  Early steps consume energy from ATP, and later steps store an increased amount of energy in ATP and NADH


In the initial stage (energy consuming), 2 ATPs and consumed to convert glucose to the high energy fructose-1,6 biphosphate. The fructose-1,6 biphosphate is later split into 2 glyceraldehyde-3-phosphate (G3P). In the energy-releasing phase, each G3P is used to generate 2 ATPs and an NADH are released. Therefore, there is a net positive energy of 2 ATPs and 2 NADHs.


Glycolysis is described as having an energy investment phase and an energy payoff because early steps consume energy from ATP, and later steps store an increased amount of energy in ATP and NADH.

Cellular respiration has three main stages: glycolysis, the Krebs cycle and oxidative phosphorylation.

Glycolysis is the first stage of cellular respiration, which uses glucose to produce energy (ATP), the reduced form of nicotinamide adenine dinucleotide (NADH) and piruvate.

During glycolysis, four molecules of ATP are produced, but the total gain of this stage is two molecules of ATP because the other two molecules of ATP are consumed in the first half of this stage.

Glycolysis also produces 2 molecules of NADH, and 2 molecules of pyruvate, which enter the Krebs cycle to produce more energy in the form of ATP.

In conclusion, glycolysis is described as having an energy investment phase and an energy payoff because early steps consume energy from ATP, and later steps store an increased amount of energy in ATP and NADH.

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