A regular toilet uses = 3.2 gallons of water per flush.
So, after 375 flushes, water used will be = [tex]3.2\times375=1200[/tex] gallons
A low flow toilet uses = 1.6 gallons of water per flush.
So, after 375 flushes, water used will be = [tex]1.6\times375=600[/tex] gallons
Hence, the difference between the number of gallons used by the regular toilet and the low flow toilet after 375 flushes = [tex]1200-600[/tex] = 600 gallons