Answer:
Only one is made of many cells.
Explanation:
Both E. coli and oak are living things and for this reason both need energy, respond to stimulation and grow in size over time. However, E. coli is a unicellular being, meaning that it has only one cell. On the other hand, oak is a multicellular being, which means it has many cells. So the difference between them is that only one is made up of many cells.
