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Think and discuss: Suppose there are two homologous chromosomes. Each chromosome contains a single mutant allele in different parts of the chromosome. How can crossovers be beneficial in this situation? (Hint: How can you create a single, mutation-free chromosome?)

Respuesta :

Abbreviation of the chromosome is known as mutation and leads to the formation of abnormal character. The mutant gene is present at the loci of the chromosome. The position of the mutant gene can be different in each chromosome.

  • Mutation can be caused by the deletion, addition, and duplication of the genes.
  • At the time of crossing over the chromatid of homologous chromosomes pair with each other and form a new character. The fusion of two different chromosomes increases the chance of the mutant free chromosome.
  • The different position of the mutant genes has fewer chances to pair together after the time of crossing over.

Therefore, we can conclude that Crossing over leads to the formation of the mutant free chromosome.

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In this case, recombination generates one chromosome containing both mutations and one chromosome without mutations. This situation could be beneficial if the combination of mutations restores the normal phenotype.

Crossing over, also known as genetic recombination, can be defined as the interchange of genetic material (DNA) between non-sister chromatids during meiosis (prophase I).

Genetic recombination increases genetic diversity by combining nucleotide sequences between homo-logous chromosomes.

In the example above, recombination generates a new chromosome containing two mutations and a new chromosome without mutations.

This situation could be beneficial if the combination of both mutations in the same genetic background are able to restore the normal phenotype (for example, by restoring the normal open reading frame of a protein-coding gene).

In conclusion, in this case, recombination generates one chromosome containing both mutations and one chromosome without mutations. This situation could be beneficial if the combination of mutations restores the normal phenotype.

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