Respuesta :
Answer;
d. Na+
Explanation;
- The cell membrane's main trait is its selective permeability, which means that it allows some substances to cross it easily, but not others.
- Small molecules that are non-polar (have no charge) can cross the membrane easily through diffusion, but ions (charged molecules) and larger molecules typically cannot.
- Charged ions such as N+ and K+ Cannot permeate the cell membrane for the since uncharged molecules repel uncharged molecules present in the membrane structure.
Na+ is the substance which would have the most trouble crossing a biological membrane through diffusion.
What is Diffusion?
This is the movement of a substance from a region of higher concentration to that of a lower concentration.
Polar and charged substances typically have most difficulty passing through a lipid bilayer due to repulsive actions thereby making option D the most appropriate choice.
Read more about Diffusion here https://brainly.com/question/852767