Answer:
cAMP in the cytoplasm
Explanation:
Water-solubile hormons cannot pass through the cell membrane, so they bind to their transmembrane receptors. As a result of their binding, receptor changes its shape (conformational change) and a signal cascade in the cytoplasm begins. Signal cascade includes the activation of primary and secondary messengers. Camp is a molecule often generated as a second messenger with the roleto amplify the signal in response to hormone binding.
