Which of the following statements is true? (a) Extracellular signal molecules that are hydrophilic must bind to a cell-surface receptor so as to signal a target cell to change its behavior. (b) To function, all extracellular signal molecules must be transported by their receptor across the plasma membrane into the cytosol. (c) A cell-surface receptor capable of binding only one type of signal molecule can mediate only one kind of cell response. (d) Any foreign substance that binds to a receptor for a normal signal molecule will always induce the same response that is produced by that signal molecule on the same cell type.

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Answer:

Its option 'A'.

Explanation:

extracellular signal molecules that are hydrophilic must bind to a cell-surface receptor so as to signal a target cell to change its behavior.

For Example:

Acetylcholine acts at a GPCR on heart muscle to make the heart beat more slowly.

The following statements is true - (a) Extracellular signal molecules that are hydrophilic must bind to a cell-surface receptor so as to signal a target cell to change its behavior

Extracellular signals:

Signals that originate from outside a cell

physical agents like mechanical pressure, voltage, temperature, light, or chemical

  • These are hydrophobic signals that can not cross the cell membrane
  • Bind to the specific signal receptor to target cell in order to initiate changes in cell function.
  • For instance, neurotransmitters are hydrophilic molecules that bind to cell surface receptors.
  • As neurotransmitters are hydrophilic molecules, they are unable to cross the plasma membrane of their target cells.

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