Answer:
The correct answers are all of them: A) "Thiamine pyrophosphate (TPP)", B) Lipoic acid (lipoamide), C) "Flavin adenine dinucleotide (FAD)", D) "Nicotinamide adenine dinucleotide (NAD+)" and E) "Coenzyme A (Co-A)".
Explanation:
The pyruvate dehydrogenase complex (PDC) is comprised of three enzymes that converts pyruvate into acetyl-CoA by a series of reactions where different coenzymes participate. During the reaction process: Thiamine pyrophosphate (TPP) is used as prosthetic group by Pyruvate dehydrogenase; Lipoic acid (lipoamide) and Coenzyme A (Co-A) are used as prosthetic group by Dihydrolipoyl transacetylase; and Flavin adenine dinucleotide (FAD) and Nicotinamide adenine dinucleotide (NAD+) are used as cofactor by Dihydrolipoyl dehydrogenase.
