Answer: The correct answer would be histone.
Explanation:
Histone proteins are the alkaline proteins mainly found in the nucleus of the eukaryotic cell.
It helps in packaging of chromatin fiber in the form of nucleosome.
The DNA molecule run around the histone proteins to form a bead-on-string conformation.
Five types of histones are involved in DNA packaging at this stage, namely: H1/H5, H2A, H2B, H3, and H4.
The first level of DNA organization in a eukaryotic cell is maintained by histone.
In eukaryotic cells, the genetic material DNA is linear and tightly bound to special proteins called histones.
In turn, each DNA molecule with its histones constitutes a chromosome and its histones represents almost half the size of the chromosome.
Histones are basic proteins, rich in lysine and arginine residues, which show high evolutionary conservatism.
Chromatin, which is the set of chromosomes in a cell, histones interact with DNA forming a subunit that repeats itself throughout the chromatin called nucleosome.
The nucleosome is the first level of DNA organization and is formed by an octamer of histones in which there are two subunits of histones H2A, H2B, H3 and H4, while histone H1 acts as a bridge (linker) between contiguous octamers.
Therefore, we can conclude that the first level of DNA organization in a eukaryotic cell is maintained by histone.
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