Answer:
The last option is the correct order of events in mitosis.
Explanation:
The metaphase stage initiated with the arrangement of sister chromatids on the metaphase plate. Post arrangement, the spindle fibers come and combine with the chromatids kinetochore. The cohesion proteins assist in the robust attachment of the spindle fibers and the kinetochore. After the attachment is done, the pulling of sister chromatids takes place towards the pole. The dissociation of cohesion proteins takes place, and the nucleus begins to form again and thus, a novel cell gets formed.
The correct order is 'the kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. Cohesin proteins break down and the sister chromatids separate. The nucleus reforms and the cell divides'.
The kinetochores are microtubules that bind chromosomes during cell division.
This structure (kinetochore) connects the chromosomes to microtubules from the mitotic spindle.
During metaphase, the kinetochore pulls the sister chromatids to align them at the equator plate of the cell.
The cohesins are multiprotein complexes that mediate the cohesion between sister chromatids.
These complexes (cohesins) are fundamental in order to hold sister chromatids (i.e., chromosomes) together before anaphase.
In anaphase, chromosomes are pulled toward opposite poles.
Finally, in telophase, chromosomes reach opposite poles, and a nuclear membrane forms around each set of chromosomes.
In conclusion, the correct order is 'the kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. Cohesin proteins break down and the sister chromatids separate. The nucleus reforms and the cell divides'.
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