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Tay-Sachs disease is a genetic disorder that results in the destruction of neurons due to a buildup of sphingolipids in the cells. Which organelle is malfunctioning in Tay-Sachs?

lysosome
endoplasmic reticulum
peroxisome
mitochondria

Respuesta :

Answer:

Lysosome

Explanation:

Lysosome is membrane bound organelle present in animal cells that contan different hydrolytic enzymes. Lysosome are also known as suicidal bag as they allows the digestion of bio molecules and foreign particles.

Tay-Sachs disease mainly occur due to the deposition of sphingolipid. The enzyme  hexosaminidase A, present in the lysosomes becomes inactive. The inactivity of this enzyme causes the deposition of sphingolipids.

Thus, the correct answer is option (1).