Answer:
The efflux pump is the most nonspecific to a particular class of antimicrobials.
Explanation:
Antimicrobial -
An antimicrobial , the agent which destroys or kills the microorganism or inhibits their growth .
And these microbes can even develop resistance mechanism which involves the inhibiting the accumulation of the antimicrobial drug .
This is very common among the gram - negative pathogens and hence , involve changes in the outer lipid membrane composition , porin channel concentration and porin channel selectivity .
The gram - negative and gram - positive pathogens bacteria produces efflux pumps that can actively transport the drug out of the cell and thereby prevents the accumulation of the the drug .