Answer:
""Alteration in hepatic function requires more frequent drug dosing.""
Explanation:
""Alteration in hepatic function requires more frequent drug dosing"" means change in liver or hepatic function requires more drug dosing at regular intervals. But this may lead to deteriorate the health condition of an older adult patients because more frequent dosing of medicines can do more harm to the liver of the older adult patients, since organs such as livers or kidneys are weak in old adult patients than in young patients.
Thus the answer is ""Alteration in hepatic function requires more frequent drug dosing.""