The nurse is explaining to a nursing student that allograft transplant clients need some form of immunosuppressant therapy. Which statement describes the pathophysiological reasoning behind this?
1. The treatment is indicated only if signs of transplant rejection are present.2. The treatment is a precaution; rejection in allografts seldom occurs.3. The treatment is designed to target chronic rejection, which does not occur for several weeks.4. Despite accurate tissue matching, allografts contain antigens that trigger the client's immune response.