Which mutation is harmful to the organism?

A. A Mutation Allowing Moths To Camouflage Better On Blackened Tree Bark.

B. A Mutation Making Staphylococcus Aureus Resistant To Antibiotic Methicillin.

C. A Mutation Inhibiting Human Immunodeficiency Virus From Attaching To And Entering The Cell.

D. A Mutation Causing Uncontrolled Cell Division.

E. a Mutation Giving Plant Leaves A Bitter Taste To Discourage Herbivores From Eating Them.