Answer: The polypeptide chain is likely to span the membrane seven times.
Explanation:
G-protein coupled receptor are trans membrane structure which means the the structure is present inside the cell as well as outside the cell membrane.
The amino acid sequence of the proteins reveals that the polypeptide chain has 7 hydrophobic regions so it is obvious that it will be having seven hydrophillic end.
This states that the polypeptide chain is spanning the cell membrane seven times.