What is the correct sequence of events for activation of a B cell by a T-dependent antigen? (1) The B cell binds to a cytokine and then interacts with the TH cell. (2) This causes the B cell to bind the antigen, and then the B cell is activated. (1) Immunoglobulin receptors on the B cell recognize and bind the antigen. (2) An antigen fragment in complex with MHC class 2 is displayed on the B cell's surface. (3) The MHC-antigen complex binds a receptor on a TH cell. (4) The TH cell secretes cytokines that activate the B cell. (1) Identical repeating subunits on the antigen bind to many of the antibodies on the surface of the B cell. (2) This activates the B cell. (1) The T cells bind to an antibody on the B cell. (2) The T cell secretes cytokines. (3) The B cell binds the antigen. (4) The B cell is activated by binding to the antigen.

Question

08-11-2019
Biology

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What is the correct sequence of events for activation of a B cell by a T-dependent antigen? (1) The B cell binds to a cytokine and then interacts with the TH cell. (2) This causes the B cell to bind the antigen, and then the B cell is activated. (1) Immunoglobulin receptors on the B cell recognize and bind the antigen. (2) An antigen fragment in complex with MHC class 2 is displayed on the B cell's surface. (3) The MHC-antigen complex binds a receptor on a TH cell. (4) The TH cell secretes cytokines that activate the B cell. (1) Identical repeating subunits on the antigen bind to many of the antibodies on the surface of the B cell. (2) This activates the B cell. (1) The T cells bind to an antibody on the B cell. (2) The T cell secretes cytokines. (3) The B cell binds the antigen. (4) The B cell is activated by binding to the antigen.

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virtuematane virtuematane · Answer 1 · 2019-11-11T05:37:18+01:00

Answer:

Antigens that activate B-cells with the help of T-cells are called as T-cells dependent antigens. They are called as such because they are not able to induce a humoral response in organisms that lack T-cells. B-cells response to these antigens take many days, thought antibodies generated are more versatile and have a higher affinity than those generated from T-cell independent activation.

So, the steps for activation of a B cell by a T-dependent antigen are:

(1) Immunoglobulin receptors on the B cell recognize and bind the antigen.

(2) An antigen fragment in complex with MHC class 2 is displayed on the B cell's surface.

(3) The MHC-antigen complex binds a receptor on a TH cell.

(4) The TH cell secretes cytokines that activate the B cell.

topeadeniran2 topeadeniran2 · Answer 2 · 2022-03-25T14:00:42+01:00

The steps for activation of a B cell by a T-dependent antigen are:

Immunoglobulin receptors on the B cell recognize and bind the antigen.
An antigen fragment in complex with MHC class 2 is displayed on the B cell's surface.
The MHC-antigen complex binds a receptor on a TH cell.
The TH cell secretes cytokines that activate the B cell.

What is a T-dependent antigen?

A thymus-dependent antigen simply means an immunogen that requires T cell cooperation with B cells in order to synthesize specific antibodies.

The presentation of thymus-dependent antigen to T cells should be in the context of MHC class II molecules.

Learn more about antigens on:

https://brainly.com/question/7597406