I assume that you talk about the stance that the world, having been created by God, governs itself through its own laws (not the mainstream science view). According to this vies, The "Who" and" the "why" would be the primary cause (who and why created the Universe?) and the secondary cause would be the When and How (and also why - why does this process take place? what causes it?) - when things in the Universe happen and how they happen.
However, notice that this view is rejected by the vast majority of the researchers.
