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A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. In one set of experiments, she succeeded in increasing the acetylation of histone tails in the chromatin of the cells. Which of the following results would she most likely see in these cells?
a. inactivation of the selected genes
b. increased chromatin condensation
c. decreased chromatin condensation
d. decreased binding of transcription factors

Respuesta :

Answer

D

D

explanition

decreased

luisvaschetto

The most likely result that the researcher observed in these cells is decreased chromatin condensation (Option c).

  • Epigenetic refers to the presence of certain chemical groups in DNA and associated (histone) proteins that are able to modify gene expression patterns.

  • Histone modifications include, among others, histone acetylation, histone methylation, etc.

  • Histone acetylation is generally associated with a transcriptionally active state by chromatin decondensation.

In conclusion, the most likely result that the researcher observed in these cells is decreased chromatin condensation (Option c).

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