Answer:
Developed in response to the use of methicillin
Explanation:
S. aureus is an opportunist gram-positive coccus, this means that it doesn't represent a problem for a healthy individual but can cause many illnesses in vulnerable populations such as hospital patients.
At the beginning of time, they were attacked with penicillin but soon they developed an enzyme named a β-lactamase, which inactivated the β-lactam and therefore the antibiotic. This led to the creation of the methicilin, unfortunately, some species became resistant to it as well by acquiring an additional penicillin-binding protein (PBP2a) from other species.
I hope you find this information useful and interesting! Good luck!