As with any drug, aspirin (acetylsalicylic acid) must remain in the bloodstream long enough to be effective. Assume that the removal of aspirin from the bloodstream into the urine is a first-order reaction, with a half-life of about 3 hours. The instructions on an aspirin bottle say to take 1 or 2 tablets every 4 hours. If a person takes 1 aspirin tablet, how much aspirin remains in the bloodstream when it is time for the second dose? (A standard tablet contains 400. mg of aspirin.)

Respuesta :

Answer:

180 mg

Explanation:

For a first-order reaction, we can calculate the amount of aspirine (A) at a certain time (t) using the following expression.

[tex]A=A_{0}.e^{-k.t}[/tex]

where,

k: rate constant

A₀: initial amount

If we know the half-life ([tex]t_{1/2}[/tex]) we can calculate the rate constant.

[tex]k=\frac{ln2}{t_{1/2}} =\frac{ln2}{3h} =0.2h^{-1}[/tex]

When t = 4 h and A₀ = 400 mg, A is:

[tex]A=400mg.e^{-0.2h^{-1}\times 4h} =180mg[/tex]