As a protein is broken down into smaller and smaller fragments, each fragment ultimately requires splitting of the last peptide bond within it. The breaking of the bond between those last two amino acids is catalyzed by the enzyme__________.

Proteins are the polymers of amino acids. Digestion of proteins starts in the stomach where the enzyme pepsin breaks down the proteins into peptides (proteoses and peptones). Similarly, the pancreatic enzyme namely trypsin, chymotrypsin, carboxypeptidase, and elastase breakdown the partially digested proteins into the dipeptides in the small intestine. Aminopeptidase and dipeptidase are the peptidases of brush border that completes the process of protein digestion. Dipeptidase serves to break the dipeptides (having two amino acids joined by a peptide bond) into single amino acids.