Second-generation H1 antagonists cause less CNS depression because they are selective for peripheral H1 receptors and because of which other property?

Respuesta :

Answer:

THEIR INABILITY TO CROSS THE BLOOD-BRAIN BARRIER AT THERAPEUTIC LEVELS.

Explanation:

Second-generation antihistamines (e.g., loratadine, terfenadine) lack the ability to pass through the blood-brain barrier at certain therapeutic levels.