Coat color in rabbits is under the control of a single gene with
four alleles: C (full gray color); cch (chinchilla, light gray); ch
(Himalayan, white with black extremities); and c (albino, absence
of pigmentation). The dominance hierarchy is represented as: C >
cch > ch > c. A series of matings involving six different
rabbits produced the following offspring:




Cross


Offspring




a. Gray-1 x gray-2


3/4 gray : 1/4 chinchilla




b. Gray-2 x gray-3


3/4 gray : 1/4 chinchilla




c. Gray-1 x chinchilla-1


1/2 gray : 1/4 chinchilla : 1/4 himalayan




d. Chinchilla-2 x himalayan


1/2 chinchilla : 1/4 himalayan : 1/4 albino




Deduce the genotype of each
rabbit, to the extent that it is possible.

Respuesta :

Answer: a) Cch x   Ccch

               b)  Ccch x  Cc

               c)   Cch  x   cchch

               d)  cchc x   chc

Explanation:

Data:

  • Coat color in rabbits is under the control of a single gene with

four alleles: C (full gray color); cch (chinchilla, light gray); ch

(Himalayan, white with black extremities); and c (albino, absence

of pigmentation).

  • The dominance hierarchy is represented as: C >cch > ch > c.

Possible genotypes:

  • For full gray color: CC (Gray), Ccch (Gray-2), Cch (Gray-1), Cc (Gray-3). The allele "C" dominates over the other three alleles, so in every combination where "C" is present, the animal will be fully grayed.
  • For light gray color/Chinchilla: cchcch (Chinchilla), cchch (Chinchilla-1), cchc (Chinchilla-2). The allele "cch" dominates over "ch" and "c", but not over "C". So if the allele "C" is combined with "cch", the animal will be fully grayed, but in any other combination with "cch", the animal will be light grayed.
  • For white with black extremities/Himalayan: chch (Hymalayan), chc (Hymalayan-1). The allele "ch" that determines the Himalayan color is only dominant over the allele "c". But in combination with any other allele, "ch" behaves as a recessive one.
  • For albino: cc. In the presence of any of the other alleles, the allele "c" always behaves as a recessive one. The only possibility of getting an albino animal is if "c" combines with another "c".

Crosses:

a) Gray-1 x gray-2

    3/4 gray : 1/4 chinchilla

   

   Parental)       C ch        x        C cch

   Gamates)     C        ch           C         cch

Punnet Square)              C              cch

                           C        CC           Ccch

                           ch       Cch         cchch

F1 Genotype)    1/4  CC  

                          1/4 Cch

                          1/4 Ccch

                          1/4 cchch

F1 Phenotype)   3/4 Fully Gray animals (CC, Cch, Ccch)

                          1/4 Chinchilla animals (cchch)

b) Gray-2 x gray-3

    3/4 gray : 1/4 chinchilla

 

Parental)          C cch      x     C c

   Gamates)    C    cch           C    c

Punnet Square)            C              cch

                           C      CC            Ccch

                           c       Cc            cchc

F1 Genotype)    1/4  CC  

                         1/4 Cc

                         1/4 Ccch

                          1/4 cchc

F1 Phenotype) 3/4 Fully Gray animals (CC, Cc, Ccch)

                        1/4 Chinchilla animals (cchc)

c) Gray-1 x chinchilla-1

    1/2 gray : 1/4 chinchilla : 1/4 himalayan

Parental)           C ch        x        cchch

   Gamates)    C        ch           cch         ch

Punnet Square)           C              ch

                          cch     Ccch       cchch

                             ch       Cch         cchch

F1 Genotype)    1/4  Ccch  

                              1/4 Cch

                              1/4 cchch

                              1/4 chch

F1 Phenotype) 2/4=1/2 Fully Gray animals (Ccch, Cch)

                             1/4 Chinchilla animals (cchch)

                             1/4 Himalayan animals (chch)

d) Chinchilla-2 x himalayan

   1/2 chinchilla : 1/4 himalayan : 1/4 albino

Parental)          cchc        x         chc

   Gamates)    cch      c            ch        c

Punnet Square)           cch              c

                           ch       cchch          chc

                             c        cchc            cc

F1 Genotype)    1/4  cchch  

                         1/4 cchc

                          1/4 chc

                          1/4 cc

F1 Phenotype) 2/4=1/2 Chinchilla animals (cchch, cchc)

                             1/4 Himalayan animals (chc)

                             1/4  Albino animals (cc)