Determining that the study has a maximization of benefits and a minimization of risks is the best example of how the Principle of Beneficence can be applied to a study employing human subjects.
The principle of beneficence demands that the human subjects have self-determination. Also if some of the human subjects do not have the power to take decisions, the investigators should make sure that the human subjects are not harmed. The researchers should increase the chances of benefits and decrease the amount of risk.
The research studies which include human subjects, even those that have very little risk should not be taken into consideration if it does not create scientifically valid or presents us new facts. It is very confusing for the researchers to determine when the benefits should be taken into consideration because of the risks and benefits should be sought despite the risks.
