Answer:
Naïve T cells
Explanation:
A naive T cell (Th0 cell) is a T cell that has characterised in bone marrow, and majorly passed through the positive and negative activities of central election in the thymus. Explamples includes the naive kinds of helper T cells (CD4+) and cytotoxic T cells (CD8+).
Naive T cells go through the thymus and into the secondary lymphoid organs. In secondary lymphoid organs, naïve T cells are stimulated by mature dendritic cells. T cell stimulation involves 2 signals: TCR and costimulation. Absence of costimulation during T cell activation produces anergy.
Mature T cells are developed in the thymus and delivered into the bloodstream in low amounts. They are known to be immunologically naïve before it encounters MHC-peptide complexes in which its T-cell receptors (TCR) have high attraction.
