Answer:
Hypothesis.
Explanation:
The science mainly deals with the study of the nature and the natural phenomena. Different fields of science are chemistry, biology, physics, geology and maths.
Hypothesis may be defined as the complete explanation of the particular phenomena mainly on the observation of the individual. A scientific hypothesis can be converted into a theory if tested by the scientific experiments. Here, Edward Jenner based on his observation predicts the hypothesis about vaccination.
Thus, the correct answer is option (A).