Answer:
In relation to voltage-gated ion channels, when depolarization occurs, Na⁺ gates open while K⁺ gates remain closed.
Explanation:
Depolarization is a phenomenon that occurs in cells like neurons, and depends on the distribution of ions in extracellular spaces and intraceluar.
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Na⁺ is a predominantly extracellular cation.
- K⁺ has a high intracellular concentration.
This distribution occurs when the membrane potential is at rest, with a negative intracellular value.
Depolarization involves opening the Na⁺ channels, so that this cation enters the intracellular space, causing a change in cell voltage. Increasing Na⁺ concentration in intracellular space progressively produces an action potential, resulting in an electrical signal.
While depolarization occurs, K⁺ channels remain closed, limiting the output of this cation to extracellular space, which would prevent the action potential from occurring.
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