Answer:
Yes, 2,4-dinitrophenol (DNP) was first used on factory workers in the 1930s and it helped them lose weight.
Explanation:
2,4-dinitrophenol (DNP):
- DNP is an anti-obesity drug that works by shuttling the movement of protons across the mitochondrial membrane, shifting the electrochemical gradient. This process is called uncoupling oxidative phosphorylation.
- Uncoupling oxidative phosphorylation increases the body's metabolic rate and inhibits the production of ATP through oxidative phosphorylation. This forces the body to produce ATP by metabolizing stored fat.