A selective mechanism that is responsible for endocytosis and transcytosis of the small amounts of materials that are present in the extracellular fluid is known as receptor-mediated endocytosis.
The various molecules that can be taken up by this process include hormones, metabolites, proteins as well as certain viruses.
This process is also known as clathrin-mediated endocytosis.
In this process, the receptors that are present on the surface of the proteins are captured by a molecule which is the target site for the protein and internalized by membrane internalization (endocytosis).
The vesicle formed by endocytosis is a clathrin coated vesicle.