Answer:
The correlation coefficient is often used as a way of estimating the divergence of gene expression profiles between varying species.
A negative correlation coefficient shows that as values on one variable advances, the values on the other variable decline. A positive correlation coefficient indicates a direct, positive relationship.
This scenario shows that Patient 4 and Mike Smith gene expressions acts in opposite ways. The number shows that Mike Smith's cancer will not show positive result as it ought to be in response to Drug 4 since its coefficient is negative.