Some applications in biology, such as polymerase chain reaction (PCR), require melting the DNA double helix into single strands of DNA. This can be accomplished by heating the DNA. As DNA is heated, why does the double helix structure denature into single strands of DNA but not into individual nucleotides? In other words, why do the single strands remain intact even though the double helix does not?
Choose one:
A. The double helix is held together with phosphodiester bonds, while the single strands are linked by hydrogen bonds.
B. The single strands are wrapped around histones, which protects them from denaturing.
C. The double helix is held together with hydrogen bonds, while the single strands are linked by phosphodiester bonds.
D. The double helix structure is important for DNA replication, while the single strands carry the information.

Question

ajadegipson9877 ajadegipson9877

10-02-2020
Biology

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Some applications in biology, such as polymerase chain reaction (PCR), require melting the DNA double helix into single strands of DNA. This can be accomplished by heating the DNA. As DNA is heated, why does the double helix structure denature into single strands of DNA but not into individual nucleotides? In other words, why do the single strands remain intact even though the double helix does not?
Choose one:
A. The double helix is held together with phosphodiester bonds, while the single strands are linked by hydrogen bonds.
B. The single strands are wrapped around histones, which protects them from denaturing.
C. The double helix is held together with hydrogen bonds, while the single strands are linked by phosphodiester bonds.
D. The double helix structure is important for DNA replication, while the single strands carry the information.

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palipali964 palipali964 · Answer 1 · 2020-02-11T11:12:09+01:00

Answer:

C. The double helix is held together with hydrogen bonds, while the single strands are linked by phosphodiester bonds.

Explanation:

The double helix is formed by hydrogen bonding between the base pairs, while the single strands are linked by phosphodiester bonds.

Phosphodiester bonds are covalent bonds versus the hydrogen bonds which are noncovalent bonds. Covalent bonds are difficult to break because of electron sharing versus electrostatic attraction of hydrogen bonds.

eyitbay eyitbay · Answer 2 · 2020-02-11T23:00:10+01:00

Answer:

The two major bonds of DNA nucleotides are the weaker hydrogen bonds between the organic bases. These bonds hold the pyrimidine and purine molecules together, to form double helix of DNA structure. The hydrogen bonds are broken down during heating so that DNA double helix can unwind to initiate gene expression Thus this bond relate DNA structures to its functions.

Secondly the relatively stronger co-valent bonds ;phosphoster bonds between nucleotides molecules resits the applied heat. This should be intact because single DNA strands need to serve as template to initiate gene expression processes so that exact copies of DNA molecules is transcribed to the mRNA. e.g in transcription If these phosphodiester bonds were broken, then transcription will be hindered because the DNA template will not be available for mRNA production thus disrupting gene expression for protein synthesis and if during replication new DNA synthesis will be disrupted because of lack of DNA strands as template.

Explanation: