Answer:
4. None of the man's children will inherit the mutation
Explanation:
This is because the mutation is somatic. that is it only affect single skin tissues and not carried in the sex-cells,that is not germinal.
Only Germinal mutation that are carried in the sex-cells of either sperm or egg , and transmitted during fertilisation can be be inherited by the offspring.
However, had it mean it was no localized, but metastasis,( spread through the blood stream to the sex-cells,) then it can be inherited by the children. Besides the wife is also negative there is no chance of the kids inheriting the mutation