Glycolysis is a metabolic pathway that converts glucose into pyruvate and is observed in each of the three domains. The hexokinase family of enzymes is required during glycolysis to phosphorylate six-carbon sugars. Researchers designed a general hexokinase inhibitor that is effective in the neurons of rats.
Which of the following best predicts the effect of adding this inhibitor to a culture of plant cells?
Plant cells will be unable to perform glycolysis due to the inhibitor and will die.

Glucose is a high energy stable compound.Therefore in order to extract the stored energy for cellular use, it must be broken down. The addition of inorganic Phosphate ions(Pi) to 6-carbon glucose compound in the presence of 2ATP molecules is called Phosphorylation. This phosphorylation reaction is catalyse by Hexokinase.

The 6C-glucose is spitted to 6C-Fructose phosphate, and to 6C-fructose biphophate. The later is converted to 2molecules of 3Carbon compounds called triose phosphate.

It is during the conversion of 2-molecules of 3C- triphosphate to Pyruvate that yields 2 ATPs per molecule of glucose.

Therefore if hexokinase is inhibited , then the glucose phosphorylation can not occur. Hence the sequence of events as Glycolytic pathways that leads to production of ATP during formation of Pyruvate can not occur.

Definitely, plant cells biochemical reactions will seize, glycolytic pathways will be inhibited, ATPs will not be synthesized,leading to plant cells deaths.

Surnia Surnia · Answer 2 · 2022-01-13T18:46:45+01:00

Plant cells will be unable to perform glycolysis due to the inhibitor and will die.

Hexokinase is one of the enzymes participate initially in the process of glycolysis.
It catalyzes the phosphorylation of glucose to glucose-6-phosphate in the presence of ATP.
It is one of the rate limiting enzymes of glycolysis.
Therefore, it will limit the rate of glycolysis in plant and the plant cell will die as the glucose will be utilized completely instead of being stored as energy reservoir in the plant cell.

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