DNA methylation and histone acetylation are examples of which of the following processes? DNA methylation and histone acetylation are examples of which of the following processes? epigenetic phenomena translocation chromosomal rearrangements genetic mutation

Epigenetics involves the changes in gene expression which is not as a result of changes in an individual's DNA sequence. In other words, it is a change in an individual's phenotype, without an alteration in the genotype.

It is involved in the normal functioning of cellular processes.

Examples of epigenetics is DNA methylation ( adding of a methyl group to a section of the DNA molecule) and histone modification such as histone acetylation (adding an acetyl group to the histone).

Epigenetic changes can switch off genes, hence, prevent the expression of those genes; it can also turn on genes, hence increase the expression of those genes.

Epigenetic changes can also results to diseases such as cancer.

genewho genewho · Answer 2 · 2021-11-30T14:02:27+01:00

DNA methylation and histone acetylation are examples of epigenetic phenomena.

Epigenetic phenomena is the gene regulation mediated by modifications of the chromatin structure (genetic material packed around proteins), or as those heritable changes in gene expression that are independent of the nucleotide sequence.

The mechanisms involved in epigenetic regulation are: DNA methylation and post-translational modifications of histones.

In the normal genome, DNA methylation occurs at repeated sequences and at transposon and viral insertion sequence sites.

Histone acetylation usually occurs in histone lysine, the positive charges (+) of lysine (K) are neutralized, and it determines that the chromatin adopts a prone conformation to transcription and replication.

Therefore, we can conclude that DNA methylation and histone acetylation are examples of epigenetic phenomena.

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