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DNA molecules of different sizes are often separated with the use of a technique called electrophoresis (see Chapter 19). With this technique, DNA molecules are placed in a gel, an electrical current is applied to the gel, and the DNA molecules migrate toward the positive (+) pole of the current. What aspect of its structure causes a DNA molecule to migrate toward the positive pole?

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Answer:

Explanation:

A DNA molecule is a polymer of nucleotides, which are made up of a nitrogenous base, a sugar and a phosphate group.

The phosphate groups are negatively charged, giving the sugar-phosphate backbone a negative charge. This negative charge causes the DNA molecule to be attracted to the positive pole of the current and thus migrate towards it.

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The aspect of its structure that causes DNA to migrate toward the positive pole is this molecule is negatively charged.

  • Deoxyribonucleic acid (DNA) is a double helix molecule composed of two long chains of nucleotides.

  • Each nucleotide in DNA is composed of a deoxyribose pentose sugar, a nitrogenous base and a phosphate group.

  • This molecule (DNA) is electronegative due to the presence of phosphate groups in the consecutive nucleotides.

In conclusion, the aspect of its structure that causes DNA to migrate toward the positive pole is this molecule is negatively charged.

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