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When oligomycin is added to an actively respiring muscle cell, ATP synthase is inhibited. Which of the following predicts the effect of oligomycin on the rate of oxygen usage and the rate of electron transport through the ETC?

a) The rate of oxygen usage remains the same, but the rate of electron transport through the ETC decreases.
b) The rate of electron transport through the ETC remains the same, but the rate of oxygen usage decreases.
c) The rates of both oxygen usage and electron transport through the ETC decrease.
d) The rates of both oxygen usage and electron transport through the ETC remain the same.

Respuesta :

Answer:

C

Explanation:

1. Oligomycin is an antibiotic: it inhibits ATP synthase ( which synthesis ATP) by blocking its  F0 subunit (proton channel), which is compulsory for ATP synthesis.  

2. By the use of  oligomycin , oxygen consumption stops because oligomycin inhibits ATP synthesis, which is coupled to the activity of the electron-transport chain.

3. The inhibition of ATP synthesis would also stop electron transport chain (ETC), reason is that the high proton concentration build up is not dissipated, the free energy is not enough to pump  protons against the increased gradient.

luisvaschetto

The statement ''the rates of both oxygen usage and electron transport through the ETC decrease' BETTER predicts the effects of oligomycin (Option c).

  • Cellular respiration is a series of metabolic reactions by which cells can produce energy (i.e., ATP) by using the chemical energy from foods and oxygen.

  • Cellular respiration can be divided into three main phases: glycolysis, the citric acid cycle and oxidative phosphorylation.

  • During oxidative phosphorylation, the transport of electrons through a series of carries is coupled to the generation of an electrochemical gradient across the inner mitochondrial membrane, which is subsequently used to synthesize ATP by the ATP synthase.

  • Oxygen is the last acceptor in the electron transport chain, thereby a drug (in this case, oligomycin) that inhibits ATP synthase will decrease both electron transport and oxygen usage.

In conclusion, the statement ''the rates of both oxygen usage and electron transport through the ETC decrease' BETTER predicts the effects of oligomycin (Option c).

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https://brainly.com/question/13520255

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