4) Which of the following statements about B-cells is incorrect?
A) B-cells differentiate into plasma cells when activated
B) B-cells require an antigen to be presented to them by other cells
C) B-cells have membrane bound antibodies called B-cell receptors
D) B-cells participate in humoral immunity
It's the T-cells that need the antigens to be presented to them for activation, via antigen presenting cells (APCs), like macrophages, dendritic cells and even B- cells themselves.